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This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicityThe risk increases if you are also taking other drugs that increase serotoninso tell your doctor or pharmacist of all the drugs you takesee Drug Interactions sectionGet medical help right away if you develop some of the following symptomsfast heartbeathallucinationsloss of coordinationsevere dizzinesssevere nausea/vomiting/diarrheatwitching musclesunexplained feverunusual agitation/restlessness.

Patients should be cautioned about the risk of bleeding associated with the concomitant use of fluoxetine and NSAIDsaspirinwarfarinor other drugs that affect coagulationsee DRUG INTERACTIONS

Neonates exposed to fluoxetine and other SSRIs or serotonin and norepinephrine reuptake inhibitorsSNRIslate in the third trimester have developed complications requiring prolonged hospitalizationrespiratory supportand tube feedingSuch complications can arise immediately upon deliveryReported clinical findings have included respiratory distresscyanosisapneaseizurestemperature instabilityfeeding difficultyvomitinghypoglycemiahypotoniahypertoniahyperreflexiatremorjitterinessirritabilityand constant cryingThese features are consistent with either a direct toxic effect of SSRIs and SNRIs orpossiblya drug discontinuation syndromeIt should be noted thatin some casesthe clinical picture is consistent with serotonin syndromesee WARNINGS AND PRECAUTIONS

Adverse Reactions Associated With Discontinuation In DepressionOCDAnd Bulimia Placebo-Controlled Us Clinical TrialsExcluding Data From Extensions Of Trials)

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcoholmarijuanaantihistaminessuch as cetirizinediphenhydraminedrugs for sleep or anxietysuch as alprazolamdiazepamzolpidemmuscle relaxantsand narcotic pain relieverssuch as codeineCheck the labels on all your medicinessuch as allergy or cough-and-cold productsbecause they may contain ingredients that cause drowsinessAsk your pharmacist about using those products safely.

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